Version 5.4
| Bos taurus Gene: RPL8 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-643432.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | RPL8 | ||||||||||
| Gene Name | 60S ribosomal protein L8 | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Gene | ENSBTAG00000026327 | ||||||||||
| Encoded Proteins |
60S ribosomal protein L8
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161016:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 14:1505030-1507633 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | |||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 76 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
SRP-dependent cotranslational protein targeting to membrane pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Peptide chain elongation pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Gene Expression pathway
Eukaryotic Translation Initiation pathway
Cap-dependent Translation Initiation pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Formation of a pool of free 40S subunits pathway
Translation pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Metabolism of proteins pathway
Nonsense-Mediated Decay (NMD) pathway
Eukaryotic Translation Termination pathway
Eukaryotic Translation Elongation pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH |
TNFalpha pathway
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| REACTOME |
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of a pool of free 40S subunits pathway
Eukaryotic Translation Termination pathway
Peptide chain elongation pathway
Eukaryotic Translation Elongation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Viral mRNA Translation pathway
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
Nonsense-Mediated Decay (NMD) pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Influenza Life Cycle pathway
Gene Expression pathway
Disease pathway
Peptide chain elongation pathway
Translation pathway
Eukaryotic Translation Termination pathway
Nonsense-Mediated Decay (NMD) pathway
Metabolism of proteins pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Cap-dependent Translation Initiation pathway
Eukaryotic Translation Initiation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Eukaryotic Translation Elongation pathway
Formation of a pool of free 40S subunits pathway
Gene Expression pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
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| KEGG |
Ribosome pathway
Ribosome pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q3T0S6 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 535056 | ||||||||||
| UniGene | Bt.48839 Bt.61907 | ||||||||||
| RefSeq | NM_001034625 XM_005215220 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | BC102277 BC151407 | ||||||||||
| GenPept | AAI02278 AAI51408 | ||||||||||
| RNA Seq Atlas | 535056 | ||||||||||