InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: VDAC1

Summary

InnateDB Gene

IDBG-645740.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

VDAC1

Gene Name

Voltage-dependent anion-selective channel protein 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013113

Encoded Proteins

IDBP-698528

Voltage-dependent anion-selective channel protein 1

IDBP-698537

Voltage-dependent anion-selective channel protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213585:
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:47247744-47273458

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000017430	ENSBTAP00000017430
ENSBTAT00000053816	ENSBTAP00000049262

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 71 interaction(s) predicted by orthology.

Predicted by orthology
Total	71 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0008308	voltage-gated anion channel activity
GO:0015288	porin activity

Biological Process

GO:0001662	behavioral fear response
GO:0006810	transport
GO:0006811	ion transport
GO:0006820	anion transport
GO:0006915	apoptotic process
GO:0007268	synaptic transmission
GO:0007270	neuron-neuron synaptic transmission
GO:0007612	learning
GO:0030855	epithelial cell differentiation
GO:0044070	regulation of anion transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005743	mitochondrial inner membrane
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042645	mitochondrial nucleoid
GO:0046930	pore complex
GO:0070062	extracellular vesicular exosome