Bos taurus Gene: VDAC1
Summary
InnateDB Gene IDBG-645740.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VDAC1
Gene Name Voltage-dependent anion-selective channel protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013113
Encoded Proteins
Voltage-dependent anion-selective channel protein 1
Voltage-dependent anion-selective channel protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213585:
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:47247744-47273458
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017430 ENSBTAP00000017430
ENSBTAT00000053816 ENSBTAP00000049262
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 71 interaction(s) predicted by orthology.
Predicted by orthology
Total 71 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0008308 voltage-gated anion channel activity
GO:0015288 porin activity
Biological Process
GO:0001662 behavioral fear response
GO:0006810 transport
GO:0006811 ion transport
GO:0006820 anion transport
GO:0006915 apoptotic process
GO:0007268 synaptic transmission
GO:0007270 neuron-neuron synaptic transmission
GO:0007612 learning
GO:0030855 epithelial cell differentiation
GO:0044070 regulation of anion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042645 mitochondrial nucleoid
GO:0046930 pore complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Mitochondrial protein import pathway
Metabolism of proteins pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of proteins pathway
Mitochondrial protein import pathway
Metabolism of proteins pathway
Mitochondrial protein import pathway
KEGG
Calcium signaling pathway pathway
Parkinson's disease pathway
Huntington's disease pathway
Calcium signaling pathway pathway
Parkinson's disease pathway
Huntington's disease pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.49674 Bt.92399
RefSeq NM_174485 XM_005209335 XM_005209336 XM_005209337 XM_005209338
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

(Move your mouse over the image to view a more detailed version)