InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: AJUBA

Summary

InnateDB Gene

IDBG-645865.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AJUBA

Gene Name

LIM domain-containing protein ajuba

Synonyms

JUB

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012724

Encoded Proteins

IDBP-698620

jub, ajuba homolog (Xenopus laevis)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129474:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:21699229-21708079

Strand

Forward strand

Band

Transcripts

ENSBTAT00000016915

ENSBTAP00000016915

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0045294	alpha-catenin binding
GO:0046872	metal ion binding
GO:0051015	actin filament binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001666	response to hypoxia
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0016339	calcium-dependent cell-cell adhesion
GO:0030032	lamellipodium assembly
GO:0030334	regulation of cell migration
GO:0031047	gene silencing by RNA
GO:0031328	positive regulation of cellular biosynthetic process
GO:0031334	positive regulation of protein complex assembly
GO:0033673	negative regulation of kinase activity
GO:0033674	positive regulation of kinase activity
GO:0034613	cellular protein localization
GO:0035195	gene silencing by miRNA
GO:0035313	wound healing, spreading of epidermal cells
GO:0035331	negative regulation of hippo signaling
GO:0043087	regulation of GTPase activity
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043406	positive regulation of MAP kinase activity
GO:0046474	glycerophospholipid biosynthetic process
GO:0048041	focal adhesion assembly
GO:1900037	regulation of cellular response to hypoxia
GO:2000637	positive regulation of gene silencing by miRNA

Cellular Component

GO:0000932	cytoplasmic mRNA processing body
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm
GO:0005815	microtubule organizing center
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005925	focal adhesion
GO:0016020	membrane
GO:0030027	lamellipodium
GO:0030054	cell junction