Version 5.4
Bos taurus Gene: NOP10
Summary
InnateDB Gene IDBG-646103.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOP10
Gene Name H/ACA ribonucleoprotein complex subunit 3
Synonyms NOLA3
Species Bos taurus
Ensembl Gene ENSBTAG00000025632
Encoded Proteins
IDBP-698876
H/ACA ribonucleoprotein complex subunit 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182117:
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:28351840-28355349
Strand Forward strand
Band
Transcripts
ENSBTAT00000036177 ENSBTAP00000036040
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030515 snoRNA binding
Biological Process
GO:0001522 pseudouridine synthesis
GO:0042254 ribosome biogenesis
Cellular Component
GO:0019013 viral nucleocapsid
GO:0030529 ribonucleoprotein complex
GO:0072588 box H/ACA RNP complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000182117
View Gene Order
ENSMUSG00000027133
View Gene Order
Cross-References
SwissProt
TrEMBL Q3ZBF2
UniProt Splice Variant
Entrez Gene 616675
UniGene Bt.61719
RefSeq NM_001114521
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103378 DAAA02028380
GenPept AAI03379
RNA Seq Atlas 616675

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca