Bos taurus Gene: SPARC | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-646341.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | SPARC | ||||||||||
Gene Name | SPARC | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000014835 | ||||||||||
Encoded Proteins |
SPARC
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113140:
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. [provided by RefSeq, Dec 2011] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 7:64878194-64900828 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME |
Platelet degranulation pathway
Extracellular matrix organization pathway
Hemostasis pathway
Platelet activation, signaling and aggregation pathway
Response to elevated platelet cytosolic Ca2+ pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
Scavenging by Class H Receptors pathway
ECM proteoglycans pathway
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KEGG | |||||||||||
INOH | |||||||||||
PID NCI | |||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH |
TGF_beta_Receptor pathway
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REACTOME |
Platelet degranulation pathway
Response to elevated platelet cytosolic Ca2+ pathway
Scavenging by Class H Receptors pathway
Extracellular matrix organization pathway
Platelet activation, signaling and aggregation pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
ECM proteoglycans pathway
Hemostasis pathway
Platelet degranulation pathway
Hemostasis pathway
Extracellular matrix organization pathway
Platelet activation, signaling and aggregation pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
ECM proteoglycans pathway
Response to elevated platelet cytosolic Ca2+ pathway
Scavenging by Class H Receptors pathway
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KEGG | |||||||||||
INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | |||||||||||
UniGene | Bt.48850 Bt.66967 | ||||||||||
RefSeq | NM_174464 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | |||||||||||
GenPept | |||||||||||
RNA Seq Atlas | |||||||||||