Version 5.4
Bos taurus Gene: ALKBH1
Summary
InnateDB Gene IDBG-646901.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALKBH1
Gene Name alkylated DNA repair protein alkB homolog 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008133
Encoded Proteins
IDBP-699747
alkylated DNA repair protein alkB homolog 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100601:
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:89891033-89914239
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010693 ENSBTAP00000010693
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity
GO:0005515 protein binding
GO:0008198 ferrous iron binding
GO:0042056 chemoattractant activity
GO:0070579 methylcytosine dioxygenase activity
Biological Process
GO:0001701 in utero embryonic development
GO:0001764 neuron migration
GO:0001890 placenta development
GO:0006307 DNA dealkylation involved in DNA repair
GO:0010468 regulation of gene expression
GO:0030154 cell differentiation
GO:0031175 neuron projection development
GO:0042245 RNA repair
GO:0043524 negative regulation of neuron apoptotic process
GO:0048589 developmental growth
GO:0050918 positive chemotaxis
GO:0070989 oxidative demethylation
GO:0080111 DNA demethylation
Cellular Component
GO:0005719 nuclear euchromatin
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000100601
View Gene Order
ENSMUSG00000079036
View Gene Order
Cross-References
SwissProt
TrEMBL A7E351
UniProt Splice Variant
Entrez Gene 538733
UniGene Bt.20398
RefSeq NM_001102220
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151719 DAAA02029725
GenPept AAI51720
RNA Seq Atlas 538733

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca