Version 5.4
| Bos taurus Gene: HRH1 | |||||||||||||||||
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| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-647815.3 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | HRH1 | ||||||||||||||||
| Gene Name | histamine H1 receptor | ||||||||||||||||
| Synonyms | |||||||||||||||||
| Species | Bos taurus | ||||||||||||||||
| Ensembl Gene | ENSBTAG00000001447 | ||||||||||||||||
| Encoded Proteins |
histamine H1 receptor
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| Protein Structure | |||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196639:
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome 22:55929988-55931463 | ||||||||||||||||
| Strand | Forward strand | ||||||||||||||||
| Band | |||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Histamine receptors pathway
Amine ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Amine ligand-binding receptors pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Histamine receptors pathway
GPCR ligand binding pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Cross-References | |||||||||||||||||
| SwissProt | |||||||||||||||||
| TrEMBL | |||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | |||||||||||||||||
| UniGene | Bt.4110 | ||||||||||||||||
| RefSeq | NM_174083 | ||||||||||||||||
| HUGO | |||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | |||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| EMBL | |||||||||||||||||
| GenPept | |||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||