Version 5.4
Bos taurus Gene: TAF7
Summary
InnateDB Gene IDBG-648659.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAF7
Gene Name transcription initiation factor TFIID subunit 7
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011945
Encoded Proteins
IDBP-701382
transcription initiation factor TFIID subunit 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178913:
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:54080964-54083194
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015852 ENSBTAP00000040614
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0035035 histone acetyltransferase binding
GO:0042809 vitamin D receptor binding
GO:0044212 transcription regulatory region DNA binding
GO:0046966 thyroid hormone receptor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006352 DNA-templated transcription, initiation
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006469 negative regulation of protein kinase activity
GO:0030520 intracellular estrogen receptor signaling pathway
GO:0035067 negative regulation of histone acetylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005669 transcription factor TFIID complex
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0008024 positive transcription elongation factor complex b
GO:0033276 transcription factor TFTC complex
GO:0071339 MLL1 complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000178913
View Gene Order
ENSMUSG00000051316
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03022
Basal transcription factors pathway
mmu03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N4B6
UniProt Splice Variant
Entrez Gene 509327
UniGene Bt.11731
RefSeq NM_001046028
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020438
GenPept
RNA Seq Atlas 509327

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca