Version 5.4
Homo sapiens Gene: PRKRIR
Summary
InnateDB Gene IDBG-65090.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRKRIR
Gene Name protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
Synonyms DAP4; P52rIPK; THAP0; THAP12
Species Homo sapiens
Ensembl Gene ENSG00000137492
Encoded Proteins
IDBP-65092
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
IDBP-593735
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:76349956-76380971
Strand Reverse strand
Band q13.5
Transcripts
ENST00000260045 ENSP00000260045
ENST00000529901
ENST00000528993 ENSP00000433966
ENST00000525277
ENST00000531878
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 13 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006950 response to stress
GO:0007165 signal transduction
GO:0008285 negative regulation of cell proliferation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030753
View Gene Order
ENSBTAG00000031609
Not yet available
Cross-References
SwissProt O43422
TrEMBL B4DS64 E9PSI2
UniProt Splice Variant
Entrez Gene 5612
UniGene Hs.503315 Hs.619244
RefSeq NM_004705
HUGO HGNC:9440
OMIM 607374
CCDS CCDS8243
HPRD
IMGT
EMBL AF007393 AF081567 AK291843 AK299594 AL049970 AP002360 BC021992 BC117138 BC117140 CH471076
GenPept AAC39564 AAG01570 AAH21992 AAI17139 AAI17141 BAF84532 BAG61526 CAB43226 EAW74992 EAW74993
RNA Seq Atlas 5612

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca