Homo sapiens Gene: CACNG1
Summary
InnateDB Gene IDBG-65325.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CACNG1
Gene Name calcium channel, voltage-dependent, gamma subunit 1
Synonyms CACNLG;
Species Homo sapiens
Ensembl Gene ENSG00000108878
Encoded Proteins
calcium channel, voltage-dependent, gamma subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:67044590-67056797
Strand Forward strand
Band q24.2
Transcripts
ENST00000226021 ENSP00000226021
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005245 voltage-gated calcium channel activity
Biological Process
GO:0006810 transport
GO:0006936 muscle contraction
GO:0034765 regulation of ion transmembrane transport
GO:0070296 sarcoplasmic reticulum calcium ion transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005891 voltage-gated calcium channel complex
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
MAPK signaling pathway pathway
Cardiac muscle contraction pathway
Hypertrophic cardiomyopathy (HCM) pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Dilated cardiomyopathy pathway
INOH
GPCR Dopamine D1like receptor signaling pathway pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q06432
TrEMBL
UniProt Splice Variant
Entrez Gene 786
UniGene Hs.147989
RefSeq NM_000727
HUGO HGNC:1405
OMIM 114209
CCDS CCDS11668
HPRD 00249
IMGT
EMBL AK313852 BC069493 BC113486 BC113492 CH471099 L07738 Z19587 Z19603
GenPept AAA51904 AAH69493 AAI13487 AAI13493 BAG36580 CAA79671 CAB62573 EAW89022
RNA Seq Atlas 786