Version 5.4
Homo sapiens Gene: ACOT13
Summary
InnateDB Gene IDBG-65562.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACOT13
Gene Name acyl-CoA thioesterase 13
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112304
Encoded Proteins
IDBP-65564
acyl-CoA thioesterase 13
IDBP-601595
acyl-CoA thioesterase 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:24667035-24705065
Strand Forward strand
Band p22.3
Transcripts
ENST00000230048 ENSP00000230048
ENST00000476436
ENST00000537591 ENSP00000445552
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 14 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0047617 acyl-CoA hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0051289 protein homotetramerization
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005819 spindle
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006717
View Gene Order
ENSBTAG00000016337
Not yet available
Cross-References
SwissProt Q9NPJ3
TrEMBL
UniProt Splice Variant
Entrez Gene 55856
UniGene Hs.731605 Hs.737812
RefSeq NM_001160094 NM_018473
HUGO HGNC:20999
OMIM 615652
CCDS CCDS54972 CCDS4558
HPRD 07158
IMGT
EMBL AF155649 AF220186 AF274952 AK000508 AK309738 AL031775 BC000894
GenPept AAF67006 AAF67651 AAH00894 AAK07529 BAA91215 CAD92509
RNA Seq Atlas 55856

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca