Version 5.4
| Homo sapiens Gene: DEFB107A | |||
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| Summary | |||
| InnateDB Gene | IDBG-6592.5 | ||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||
| Gene Symbol | DEFB107A | ||
| Gene Name | defensin, beta 107A | ||
| Synonyms | |||
| Species | Homo sapiens | ||
| Ensembl Gene | ENSG00000186572 | ||
| Encoded Proteins |
defensin, beta 107A
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||
| Entrez Gene | |||
| Summary |
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107B, represents the more telomeric copy. [provided by RefSeq, Jul 2008] Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107A, represents the more centromeric copy. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||
| Type | Protein coding | ||
| Genomic Location | Chromosome 8:7811720-7815716 | ||
| Strand | Reverse strand | ||
| Band | p23.1 | ||
| Transcripts |
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| Interactions | |||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||
| No orthologs found for this gene | |||
| Pathways | |||
| NETPATH | |||
| REACTOME |
Beta defensins pathway
Defensins pathway
Innate Immune System pathway
Immune System pathway
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| KEGG | |||
| INOH | |||
| PID NCI | |||
| Cross-References | |||
| SwissProt | Q8IZN7 | ||
| TrEMBL | |||
| UniProt Splice Variant | |||
| Entrez Gene | 503614 | ||
| UniGene | Hs.520874 Hs.713490 | ||
| RefSeq | NM_001037668 | ||
| HUGO | HGNC:18086 | ||
| OMIM | |||
| CCDS | CCDS43699 | ||
| HPRD | |||
| IMGT | |||
| EMBL | AC134684 AF540979 AY122467 BC137510 BC137513 DQ119826 | ||
| GenPept | AAI37511 AAI37514 AAM93909 AAN33115 AAZ81951 | ||
| RNA Seq Atlas | 245910 503614 | ||