Homo sapiens Gene: DEFB107A | |||
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Summary | |||
InnateDB Gene | IDBG-6592.5 | ||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||
Gene Symbol | DEFB107A | ||
Gene Name | defensin, beta 107A | ||
Synonyms | |||
Species | Homo sapiens | ||
Ensembl Gene | ENSG00000186572 | ||
Encoded Proteins |
defensin, beta 107A
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Protein Structure |
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Useful resources | Stemformatics EHFPI ImmGen | ||
Entrez Gene | |||
Summary |
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107B, represents the more telomeric copy. [provided by RefSeq, Jul 2008] Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107A, represents the more centromeric copy. [provided by RefSeq, Jul 2008] |
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Gene Information | |||
Type | Protein coding | ||
Genomic Location | Chromosome 8:7811720-7815716 | ||
Strand | Reverse strand | ||
Band | p23.1 | ||
Transcripts |
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Interactions | |||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||
No orthologs found for this gene | |||
Pathways | |||
NETPATH | |||
REACTOME |
Beta defensins pathway
Defensins pathway
Innate Immune System pathway
Immune System pathway
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KEGG | |||
INOH | |||
PID NCI | |||
Cross-References | |||
SwissProt | Q8IZN7 | ||
TrEMBL | |||
UniProt Splice Variant | |||
Entrez Gene | 503614 | ||
UniGene | Hs.520874 Hs.713490 | ||
RefSeq | NM_001037668 | ||
HUGO | HGNC:18086 | ||
OMIM | |||
CCDS | CCDS43699 | ||
HPRD | |||
IMGT | |||
EMBL | AC134684 AF540979 AY122467 BC137510 BC137513 DQ119826 | ||
GenPept | AAI37511 AAI37514 AAM93909 AAN33115 AAZ81951 | ||
RNA Seq Atlas | 245910 503614 | ||