Homo sapiens Gene: ABCA9
Summary
InnateDB Gene IDBG-66095.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCA9
Gene Name ATP-binding cassette, sub-family A (ABC1), member 9
Synonyms EST640918;
Species Homo sapiens
Ensembl Gene ENSG00000154258
Encoded Proteins
ATP-binding cassette, sub-family A (ABC1), member 9
ATP-binding cassette, sub-family A (ABC1), member 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:68974488-69061064
Strand Reverse strand
Band q24.2
Transcripts
ENST00000340001 ENSP00000342216
ENST00000453985 ENSP00000394264
ENST00000482072
ENST00000460872
ENST00000492580
ENST00000461623
ENST00000495634 ENSP00000465601
ENST00000585714 ENSP00000465191
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0016887 ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
Cellular Component
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
ABCA transporters in lipid homeostasis pathway
ABC-family proteins mediated transport pathway
KEGG
ABC transporters pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL H0Y4U7 K7EJJ0
UniProt Splice Variant
Entrez Gene 10350
UniGene Hs.131686
RefSeq NM_080283 XM_005256934 XM_005256936 XM_005256937 XM_006721633 XM_006721634
HUGO HGNC:39
OMIM 612507
CCDS CCDS11681
HPRD 12401
IMGT
EMBL AC005922
GenPept
RNA Seq Atlas 10350