Version 5.4
Homo sapiens Gene: DNAJC19
Summary
InnateDB Gene IDBG-66678.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAJC19
Gene Name DnaJ (Hsp40) homolog, subfamily C, member 19
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000205981
Encoded Proteins
IDBP-66680
DnaJ (Hsp40) homolog, subfamily C, member 19
IDBP-477747
DnaJ (Hsp40) homolog, subfamily C, member 19
IDBP-476336
DnaJ (Hsp40) homolog, subfamily C, member 19
IDBP-475784
DnaJ (Hsp40) homolog, subfamily C, member 19
IDBP-482575
DnaJ (Hsp40) homolog, subfamily C, member 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:180983709-180989774
Strand Reverse strand
Band q26.33
Transcripts
ENST00000382564 ENSP00000372005
ENST00000469657 ENSP00000418058
ENST00000486355 ENSP00000419991
ENST00000491873 ENSP00000420767
ENST00000479269 ENSP00000419191
ENST00000478723
ENST00000485675
ENST00000482363
ENST00000472504
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006457 protein folding
GO:0006626 protein targeting to mitochondrion
GO:0007601 visual perception
GO:0044267 cellular protein metabolic process
GO:0048806 genitalia development
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027679
View Gene Order
ENSBTAG00000023513
Not yet available
Pathways
NETPATH
REACTOME
REACT_118595
Mitochondrial protein import pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001190233 NM_145261
HUGO
OMIM
CCDS CCDS33895 CCDS54684
HPRD 12349
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca