Homo sapiens Gene: ATP11B
Summary
InnateDB Gene IDBG-66738.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP11B
Gene Name ATPase, class VI, type 11B
Synonyms ATPIF; ATPIR;
Species Homo sapiens
Ensembl Gene ENSG00000058063
Encoded Proteins
ATPase, class VI, type 11B
ATPase, class VI, type 11B
ATPase, class VI, type 11B
ATPase, class VI, type 11B
ATPase, class VI, type 11B
ATPase, class VI, type 11B
ATPase, class VI, type 11B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:182793500-182921635
Strand Forward strand
Band q26.33
Transcripts
ENST00000323116 ENSP00000321195
ENST00000493826 ENSP00000419032
ENST00000482794
ENST00000498086 ENSP00000418421
ENST00000490303
ENST00000466758 ENSP00000417406
ENST00000482070 ENSP00000417124
ENST00000491699 ENSP00000419768
ENST00000484691 ENSP00000419152
ENST00000475636
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004012 phospholipid-translocating ATPase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015075 ion transmembrane transporter activity
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding
Biological Process
GO:0006811 ion transport
GO:0006812 cation transport
GO:0008152 metabolic process
GO:0015914 phospholipid transport
GO:0015917 aminophospholipid transport
GO:0034220 ion transmembrane transport
GO:0045332 phospholipid translocation
GO:0055085 transmembrane transport
Cellular Component
GO:0005637 nuclear inner membrane
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
Ion channel transport pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.478429 Hs.619369
RefSeq NM_014616 XM_005247243
HUGO
OMIM
CCDS CCDS33896
HPRD 10432
IMGT
EMBL
GenPept
RNA Seq Atlas