Homo sapiens Gene: LAMP3
Summary
InnateDB Gene IDBG-66856.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LAMP3
Gene Name lysosomal-associated membrane protein 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000078081
Encoded Proteins
lysosomal-associated membrane protein 3
lysosomal-associated membrane protein 3
lysosomal-associated membrane protein 3
lysosomal-associated membrane protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:183122213-183163839
Strand Reverse strand
Band q27.1
Transcripts
ENST00000265598 ENSP00000265598
ENST00000466939 ENSP00000418912
ENST00000476015 ENSP00000419059
ENST00000470251 ENSP00000420589
ENST00000486686
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002376 immune system process
GO:0008283 cell proliferation
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0097233 alveolar lamellar body membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Lysosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.518448 Hs.619233
RefSeq NM_014398
HUGO
OMIM
CCDS CCDS3242
HPRD 12062
IMGT
EMBL
GenPept
RNA Seq Atlas