InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL38

Summary

InnateDB Gene

IDBG-66980.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL38

Gene Name

ribosomal protein L38

Synonyms

L38

Species

Homo sapiens

Ensembl Gene

ENSG00000172809

Encoded Proteins

IDBP-66982

ribosomal protein L38

IDBP-384005

ribosomal protein L38

IDBP-764879

IDBP-592028

ribosomal protein L38

IDBP-758425

IDBP-758298

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L38E family of ribosomal proteins. It is located in the cytoplasm. Alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome, including one located in the promoter region of the type 1 angiotensin II receptor gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:74203582-74210655

Strand

Forward strand

Band

q25.1

Transcripts

ENST00000311111	ENSP00000309830
ENST00000439590	ENSP00000390279
ENST00000530646
ENST00000529123
ENST00000534490	ENSP00000462837
ENST00000533498	ENSP00000434243
ENST00000528433	ENSP00000462580
ENST00000584577	ENSP00000463312

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 83 experimentally validated interaction(s) in this database.

Experimentally validated
Total	83 [view]
Protein-Protein	83 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0001501	skeletal system development
GO:0001503	ossification
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006417	regulation of translation
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0007605	sensory perception of sound
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0034463	90S preribosome assembly
GO:0042474	middle ear morphogenesis
GO:0044267	cellular protein metabolic process
GO:0048318	axial mesoderm development