Version 5.4
Homo sapiens Gene: PRSS23
Summary
InnateDB Gene IDBG-67021.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRSS23
Gene Name protease, serine, 23
Synonyms SIG13; SPUVE; ZSIG13
Species Homo sapiens
Ensembl Gene ENSG00000150687
Encoded Proteins
IDBP-67023
protease, serine, 23
IDBP-603672
protease, serine, 23
IDBP-599950
protease, serine, 23
IDBP-596333
protease, serine, 23
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the trypsin family of serine proteases. Mouse studies found a decrease of mRNA levels after ovulation was induced. This gene seems to be highly conserved in vertebrates and may be an important ovarian protease. [provided by RefSeq, Jul 2008]
This gene encodes a conserved member of the trypsin family of serine proteases. Mouse studies found a decrease of mRNA levels of this gene after ovulation was induced. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:86791059-86952910
Strand Forward strand
Band q14.2
Transcripts
ENST00000280258 ENSP00000280258
ENST00000527521 ENSP00000435951
ENST00000532234 ENSP00000436676
ENST00000533902 ENSP00000437268
ENST00000531475
ENST00000533880
ENST00000532572
ENST00000528769
ENST00000531521
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
Experimentally validated
Total 28 [view]
Protein-Protein 27 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005634 nucleus
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039405
View Gene Order
ENSBTAG00000015177
Not yet available
Cross-References
SwissProt
TrEMBL E9PMX2
UniProt Splice Variant
Entrez Gene 11098
UniGene Hs.25338 Hs.603497 Hs.622241 Hs.729257
RefSeq NM_001293179 NM_001293180 NM_007173 XM_005273727
HUGO HGNC:14370
OMIM
CCDS CCDS8278
HPRD 07149
IMGT
EMBL AP000654 AP001528
GenPept
RNA Seq Atlas 11098

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca