Homo sapiens Gene: MGAT5B
Summary
InnateDB Gene IDBG-70155.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MGAT5B
Gene Name mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167889
Encoded Proteins
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:76868456-76950393
Strand Forward strand
Band q25.2
Transcripts
ENST00000301618 ENSP00000301618
ENST00000374998
ENST00000428789 ENSP00000391227
ENST00000569840 ENSP00000456037
ENST00000565043 ENSP00000455631
ENST00000563627
ENST00000563153
ENST00000568598
ENST00000565675 ENSP00000457614
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006487 protein N-linked glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
N-Glycan biosynthesis pathway
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.144531
RefSeq NM_001199172 NM_144677 NM_198955 XM_006721707 XM_006721708
HUGO
OMIM
CCDS CCDS11751 CCDS45788 CCDS59299
HPRD 14392
IMGT
EMBL
GenPept
RNA Seq Atlas