Homo sapiens Gene: MGAT5B
Summary
InnateDB Gene IDBG-70155.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MGAT5B
Gene Name mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167889
Encoded Proteins
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:76868456-76950393
Strand Forward strand
Band q25.2
Transcripts
ENST00000301618 ENSP00000301618
ENST00000374998
ENST00000428789 ENSP00000391227
ENST00000569840 ENSP00000456037
ENST00000565043 ENSP00000455631
ENST00000563627
ENST00000563153
ENST00000568598
ENST00000565675 ENSP00000457614
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006487 protein N-linked glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
N-Glycan biosynthesis pathway
Other types of O-glycan biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.144531
RefSeq NM_001199172 NM_144677 NM_198955 XM_006721707 XM_006721708
HUGO
OMIM
CCDS CCDS11751 CCDS45788 CCDS59299
HPRD 14392
IMGT
EMBL
GenPept
RNA Seq Atlas