Homo sapiens Gene: DNAAF3
Summary
InnateDB Gene IDBG-70245.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAAF3
Gene Name dynein, axonemal, assembly factor 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167646
Encoded Proteins
chromosome 19 open reading frame 51
chromosome 19 open reading frame 51
chromosome 19 open reading frame 51
chromosome 19 open reading frame 51
chromosome 19 open reading frame 51
chromosome 19 open reading frame 51
chromosome 19 open reading frame 51
chromosome 19 open reading frame 51
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is required for the assembly of axonemal inner and outer dynein arms and plays a role in assembling dynein complexes for transport into cilia. Defects in this gene are a cause of primary ciliary dyskinesia type 2 (CILD2). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:55158661-55166722
Strand Reverse strand
Band q13.42
Transcripts
ENST00000391720 ENSP00000375600
ENST00000455045 ENSP00000394343
ENST00000528412 ENSP00000433826
ENST00000533527
ENST00000524407 ENSP00000432046
ENST00000527292
ENST00000526959
ENST00000527166
ENST00000526003 ENSP00000473009
ENST00000527223 ENSP00000436975
ENST00000534170 ENSP00000432360
ENST00000532817 ENSP00000432838
ENST00000534214 ENSP00000433247
ENST00000528476
ENST00000586877
ENST00000588076 ENSP00000472645
ENST00000587789
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0044458 motile cilium assembly
GO:0070286 axonemal dynein complex assembly
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.351582 Hs.714516
RefSeq NM_001256714 NM_001256715 NM_001256716 NM_178837
HUGO
OMIM
CCDS CCDS12918 CCDS58679 CCDS58680 CCDS59422
HPRD 14185
IMGT
EMBL
GenPept
RNA Seq Atlas