Version 5.4
Homo sapiens Gene: YSK4
Summary
InnateDB Gene IDBG-70647.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YSK4
Gene Name mitogen-activated protein kinase kinase kinase 19
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176601
Encoded Proteins
IDBP-70649
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
IDBP-70651
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
IDBP-70653
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
IDBP-244673
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
IDBP-244675
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
IDBP-244677
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
IDBP-386117
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
IDBP-386120
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
IDBP-386122
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:134964491-135047468
Strand Reverse strand
Band q21.3
Transcripts
ENST00000375845 ENSP00000365005
ENST00000358371 ENSP00000351140
ENST00000375844 ENSP00000365004
ENST00000392918 ENSP00000376650
ENST00000392917 ENSP00000376649
ENST00000392915 ENSP00000376647
ENST00000437365 ENSP00000392827
ENST00000425952 ENSP00000390940
ENST00000414343 ENSP00000416345
ENST00000478805
ENST00000468155
ENST00000486077
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0000165 MAPK cascade
GO:0000186 activation of MAPKK activity
GO:0006468 protein phosphorylation
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000051590
View Gene Order
ENSBTAG00000014409
Not yet available
Cross-References
SwissProt Q56UN5
TrEMBL C9JEJ9 C9JGQ2
UniProt Splice Variant
Entrez Gene 80122
UniGene Hs.659395 Hs.739490
RefSeq NM_001282883 NM_001018044 NM_001018046 NM_001018047 NM_025052 XM_006712774
HUGO HGNC:26249
OMIM
CCDS CCDS63021 CCDS2176 CCDS33293 CCDS63020 CCDS63022
HPRD 08016
IMGT
EMBL AC016725 AC020602 AK026727 AY574901 AY574902 AY574903 AY574904 AY574905 BC034417 BC137276 BC137277 BC144555
GenPept AAH34417 AAI37277 AAI37278 AAI44556 AAT81410 AAT81411 AAT81412 AAT81413 AAT81414 AAY14999 BAB15538
RNA Seq Atlas 80122

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca