Version 5.4
Homo sapiens Gene: UBXN4
Summary
InnateDB Gene IDBG-70857.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBXN4
Gene Name UBX domain protein 4
Synonyms erasin; UBXD2; UBXDC1
Species Homo sapiens
Ensembl Gene ENSG00000144224
Encoded Proteins
IDBP-70859
UBX domain protein 4
IDBP-386181
UBX domain protein 4
IDBP-386182
UBX domain protein 4
IDBP-386183
UBX domain protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP; MIM 601023) and promotes ER-associated protein degradation (ERAD) (Liang et al., 2006 [PubMed 16968747]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:135741619-135785055
Strand Forward strand
Band q21.3
Transcripts
ENST00000272638 ENSP00000272638
ENST00000415164 ENSP00000401748
ENST00000426921 ENSP00000410516
ENST00000416538 ENSP00000391586
ENST00000467065
ENST00000470687
ENST00000490163
ENST00000471246
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006986 response to unfolded protein
Cellular Component
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026353
View Gene Order
ENSBTAG00000015169
Not yet available
Cross-References
SwissProt
TrEMBL C9JLR4
UniProt Splice Variant
Entrez Gene 23190
UniGene Hs.591242 Hs.595471 Hs.714555
RefSeq NM_014607 XM_006712370
HUGO HGNC:14860
OMIM 611216
CCDS CCDS42761
HPRD 18254
IMGT
EMBL AC011893
GenPept
RNA Seq Atlas 23190

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca