Homo sapiens Gene: CANT1
Summary
InnateDB Gene IDBG-71027.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CANT1
Gene Name calcium activated nucleotidase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171302
Encoded Proteins
calcium activated nucleotidase 1
calcium activated nucleotidase 1
calcium activated nucleotidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:78991717-79009867
Strand Reverse strand
Band q25.3
Transcripts
ENST00000302345 ENSP00000307674
ENST00000392446 ENSP00000376241
ENST00000590370 ENSP00000466637
ENST00000588611 ENSP00000465816
ENST00000591625 ENSP00000467777
ENST00000592228 ENSP00000466743
ENST00000586916 ENSP00000467970
ENST00000588075 ENSP00000465769
ENST00000591811 ENSP00000464841
ENST00000587242
ENST00000592887
ENST00000591732
ENST00000588096
ENST00000591773 ENSP00000467437
ENST00000592033 ENSP00000467886
ENST00000620915 ENSP00000477798
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005509 calcium ion binding
GO:0016462 pyrophosphatase activity
GO:0045134 uridine-diphosphatase activity
Biological Process
GO:0007165 signal transduction
GO:0008152 metabolic process
GO:0030166 proteoglycan biosynthetic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Purine metabolism pathway
Pyrimidine metabolism pathway
INOH
Purine nucleotides nucleosides metabolism pathway
Pyrimidine nucleotides nucleosides metabolism pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.686224 Hs.686745 Hs.739335 Hs.8859
RefSeq NM_001159772 NM_001159773 NM_138793 XM_005257020 XM_005257021 XM_005257022 XM_006721682 XM_006721683
HUGO
OMIM
CCDS CCDS11760
HPRD 13003
IMGT
EMBL
GenPept
RNA Seq Atlas