Version 5.4
Homo sapiens Gene: MTMR9
Summary
InnateDB Gene IDBG-7193.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTMR9
Gene Name myotubularin related protein 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104643
Encoded Proteins
IDBP-7197
myotubularin related protein 9
IDBP-599609
myotubularin related protein 9
IDBP-602085
myotubularin related protein 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:11284416-11328146
Strand Forward strand
Band p23.1
Transcripts
ENST00000221086 ENSP00000221086
ENST00000530200 ENSP00000436046
ENST00000526292 ENSP00000433239
ENST00000528389
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016791 phosphatase activity
GO:0030234 enzyme regulator activity
Biological Process
GO:0016311 dephosphorylation
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035078
View Gene Order
ENSBTAG00000003726
Not yet available
Cross-References
SwissProt
TrEMBL E9PR67
UniProt Splice Variant
Entrez Gene 66036
UniGene Hs.591395 Hs.598082 Hs.628435 Hs.639224
RefSeq NM_015458 XM_005272396
HUGO HGNC:14596
OMIM 606260
CCDS CCDS5979
HPRD 09377
IMGT
EMBL AF131216
GenPept
RNA Seq Atlas 66036

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca