Homo sapiens Gene: GPX6
Summary
InnateDB Gene IDBG-72122.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPX6
Gene Name glutathione peroxidase 6 (olfactory)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198704
Encoded Proteins
glutathione peroxidase 6 (olfactory)
glutathione peroxidase 6 (olfactory)
glutathione peroxidase 6 (olfactory)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:28503296-28528215
Strand Reverse strand
Band p22.1
Transcripts
ENST00000361902 ENSP00000354581
ENST00000474923 ENSP00000417364
ENST00000483058
ENST00000612264 ENSP00000483462
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004602 glutathione peroxidase activity
Biological Process
GO:0006979 response to oxidative stress
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
KEGG
Arachidonic acid metabolism pathway
Glutathione metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.448570 Hs.691056
RefSeq NM_182701
HUGO
OMIM
CCDS CCDS43432
HPRD 12132
IMGT
EMBL
GenPept
RNA Seq Atlas