Version 5.4
Homo sapiens Gene: FMNL2
Summary
InnateDB Gene IDBG-72470.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FMNL2
Gene Name formin-like 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000157827
Encoded Proteins
IDBP-72474
formin-like 2
IDBP-484926
formin-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:152335237-152649834
Strand Forward strand
Band q23.3
Transcripts
ENST00000288670 ENSP00000288670
ENST00000492942
ENST00000475377 ENSP00000418959
ENST00000497192
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0016043 cellular component organization
GO:0022604 regulation of cell morphogenesis
GO:0030036 actin cytoskeleton organization
GO:0030866 cortical actin cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036053
View Gene Order
ENSBTAG00000026851
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.638026 Hs.654630
RefSeq NM_052905 XM_006712228 XM_006712229
HUGO
OMIM
CCDS CCDS46429
HPRD 13545
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca