Homo sapiens Gene: FMNL2
Summary
InnateDB Gene IDBG-72470.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FMNL2
Gene Name formin-like 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000157827
Encoded Proteins
formin-like 2
formin-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:152335237-152649834
Strand Forward strand
Band q23.3
Transcripts
ENST00000288670 ENSP00000288670
ENST00000492942
ENST00000475377 ENSP00000418959
ENST00000497192
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0016043 cellular component organization
GO:0022604 regulation of cell morphogenesis
GO:0030036 actin cytoskeleton organization
GO:0030866 cortical actin cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL C9IZY8
UniProt Splice Variant
Entrez Gene 114793
UniGene Hs.638026 Hs.654630
RefSeq XM_006712228 NM_052905 XM_006712229
HUGO HGNC:18267
OMIM
CCDS CCDS46429
HPRD 13545
IMGT
EMBL AC012066 AC012443 AC093794
GenPept
RNA Seq Atlas 114793