Version 5.4
Homo sapiens Gene: PSAT1
Summary
InnateDB Gene IDBG-72636.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSAT1
Gene Name phosphoserine aminotransferase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000135069
Encoded Proteins
IDBP-72638
phosphoserine aminotransferase 1
IDBP-72640
phosphoserine aminotransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:78297143-78330093
Strand Forward strand
Band q21.2
Transcripts
ENST00000376588 ENSP00000365773
ENST00000347159 ENSP00000317606
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006564 L-serine biosynthetic process
GO:0008152 metabolic process
GO:0008615 pyridoxine biosynthetic process
GO:0008652 cellular amino acid biosynthetic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024640
View Gene Order
ENSBTAG00000013960
Not yet available
Pathways
NETPATH
REACTOME
REACT_115789
Serine biosynthesis pathway
REACT_238
Amino acid synthesis and interconversion (transamination) pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
KEGG
hsa00750
Vitamin B6 metabolism pathway
hsa00260
Glycine, serine and threonine metabolism pathway
INOH
INOH website
Vitamin B6 metabolism pathway
INOH website
Glycine Serine metabolism pathway
PID NCI
Cross-References
SwissProt Q9Y617
TrEMBL A0A024R280 A9LS35
UniProt Splice Variant
Entrez Gene 29968
UniGene Hs.494261
RefSeq NM_021154 NM_058179
HUGO HGNC:19129
OMIM 610936
CCDS CCDS6659 CCDS6660
HPRD 17918
IMGT
EMBL AF113132 AL353594 AY131232 BC000971 BC004863 BC016645 BC018129 BT006840 CH471089 EU257144
GenPept AAD42052 AAH00971 AAH04863 AAH16645 AAH18129 AAN71736 AAP35486 ABX55932 CAI16882 CAI16883 EAW62617 EAW62619 EAW62621
RNA Seq Atlas 29968

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca