Homo sapiens Gene: ASB12
Summary
InnateDB Gene IDBG-73147.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASB12
Gene Name ankyrin repeat and SOCS box containing 12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198881
Encoded Proteins
ankyrin repeat and SOCS box containing 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:64224196-64230631
Strand Reverse strand
Band q11.2
Transcripts
ENST00000362002 ENSP00000355195
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 28 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Adaptive Immune System pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8WXK4
TrEMBL
UniProt Splice Variant
Entrez Gene 142689
UniGene Hs.56281
RefSeq NM_130388
HUGO HGNC:19763
OMIM 300891
CCDS CCDS14378
HPRD
IMGT
EMBL AF403030 AK096896 AL356317 BC069436 BC069555 BC093883 BC104946 CH471132
GenPept AAH69436 AAH69555 AAH93883 AAI04947 AAL57349 BAC04888 CAI39932 EAX05414
RNA Seq Atlas 142689