Version 5.4
Homo sapiens Gene: ZNF446
Summary
InnateDB Gene IDBG-73392.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF446
Gene Name zinc finger protein 446
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000083838
Encoded Proteins
IDBP-73394
zinc finger protein 446
IDBP-762948
IDBP-765695
IDBP-761315
IDBP-813150
zinc finger protein 446
IDBP-813154
zinc finger protein 446
IDBP-813156
zinc finger protein 446
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:58474017-58481230
Strand Forward strand
Band q13.43
Transcripts
ENST00000335841 ENSP00000336565
ENST00000391694
ENST00000594468
ENST00000596341 ENSP00000472219
ENST00000600013 ENSP00000470963
ENST00000594369 ENSP00000472802
ENST00000622313 ENSP00000484676
ENST00000622379 ENSP00000477947
ENST00000610298 ENSP00000478778
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005615 extracellular space
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033961
View Gene Order
ENSBTAG00000038534
Not yet available
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_017908 XM_005259052
HUGO
OMIM
CCDS CCDS12982
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca