Version 5.4
Homo sapiens Gene: SCN2B
Summary
InnateDB Gene IDBG-73501.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCN2B
Gene Name sodium channel, voltage-gated, type II, beta subunit
Synonyms ATFB14
Species Homo sapiens
Ensembl Gene ENSG00000149575
Encoded Proteins
IDBP-73503
sodium channel, voltage-gated, type II, beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:118161951-118176673
Strand Reverse strand
Band q23.3
Transcripts
ENST00000278947 ENSP00000278947
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005248 voltage-gated sodium channel activity
GO:0005515 protein binding
GO:0017080 sodium channel regulator activity
GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential
Biological Process
GO:0007268 synaptic transmission
GO:0007399 nervous system development
GO:0035725 sodium ion transmembrane transport
GO:0046684 response to pyrethroid
GO:0060048 cardiac muscle contraction
GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization
GO:0086002 cardiac muscle cell action potential involved in contraction
GO:0086012 membrane depolarization during cardiac muscle cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:2000649 regulation of sodium ion transmembrane transporter activity
Cellular Component
GO:0001518 voltage-gated sodium channel complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000070304
View Gene Order
ENSBTAG00000033529
Not yet available
Pathways
NETPATH
REACTOME
REACT_22266
Interaction between L1 and Ankyrins pathway
REACT_22205
L1CAM interactions pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt O60939
TrEMBL Q5U0K8
UniProt Splice Variant
Entrez Gene 6327
UniGene Hs.129783
RefSeq NM_004588
HUGO HGNC:10589
OMIM 601327
CCDS CCDS8390
HPRD
IMGT
EMBL AF007783 AF049496 AF049497 AF049498 AF107028 AK313891 AY358945 BC036793 BT019487 CH471065 U87555
GenPept AAC05208 AAC05274 AAC26013 AAD47196 AAF21472 AAH36793 AAQ89304 AAV38294 BAG36614 EAW67353
RNA Seq Atlas 6327

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca