Homo sapiens Gene: MMD2
Summary
InnateDB Gene IDBG-7375.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MMD2
Gene Name monocyte to macrophage differentiation-associated 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136297
Encoded Proteins
monocyte to macrophage differentiation-associated 2
monocyte to macrophage differentiation-associated 2
monocyte to macrophage differentiation-associated 2
monocyte to macrophage differentiation-associated 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:4905989-4959213
Strand Reverse strand
Band p22.1
Transcripts
ENST00000404774 ENSP00000384690
ENST00000401401 ENSP00000384141
ENST00000406755 ENSP00000385963
ENST00000612910 ENSP00000484193
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0019835 cytolysis
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.558694
RefSeq NM_001100600 NM_001270375 NM_198403
HUGO
OMIM
CCDS CCDS47529 CCDS47530 CCDS59047
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas