Homo sapiens Gene: CTNNBL1
Summary
InnateDB Gene IDBG-74368.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTNNBL1
Gene Name catenin, beta like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132792
Encoded Proteins
catenin, beta like 1
catenin, beta like 1
catenin, beta like 1
catenin, beta like 1
catenin, beta like 1
catenin, beta like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs. In addition, the encoded protein contains Armadillo/beta-catenin-like repeats, which have been implicated in protein-protein interactions. Although the function of this protein has not been determined, the C-terminal portion of the protein has been shown to possess apoptosis-inducing activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:37693955-37872129
Strand Forward strand
Band q11.23
Transcripts
ENST00000361383 ENSP00000355050
ENST00000373473 ENSP00000362572
ENST00000373469 ENSP00000362568
ENST00000405275 ENSP00000384355
ENST00000447935 ENSP00000394464
ENST00000473857
ENST00000472237
ENST00000481674
ENST00000621317 ENSP00000478532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
Experimentally validated
Total 58 [view]
Protein-Protein 56 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0006397 mRNA processing
GO:0006915 apoptotic process
GO:0008380 RNA splicing
GO:0016445 somatic diversification of immunoglobulins
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
KEGG
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 56259
UniGene
RefSeq NM_030877 NM_001281495
HUGO HGNC:15879
OMIM 611537
CCDS CCDS13298
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 56259