Version 5.4
Homo sapiens Gene: TRIM29
Summary
InnateDB Gene IDBG-74574.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM29
Gene Name tripartite motif containing 29
Synonyms ATDC
Species Homo sapiens
Ensembl Gene ENSG00000137699
Encoded Proteins
IDBP-74578
tripartite motif containing 29
IDBP-584906
tripartite motif containing 29
IDBP-598983
tripartite motif containing 29
IDBP-583733
tripartite motif containing 29
IDBP-589010
tripartite motif containing 29
IDBP-593544
tripartite motif containing 29
IDBP-602687
tripartite motif containing 29
IDBP-590653
tripartite motif containing 29
IDBP-584102
tripartite motif containing 29
IDBP-590778
tripartite motif containing 29
IDBP-584166
tripartite motif containing 29
IDBP-585159
tripartite motif containing 29
IDBP-598257
tripartite motif containing 29
IDBP-599194
tripartite motif containing 29
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120111275-120185529
Strand Reverse strand
Band q23.3
Transcripts
ENST00000341846 ENSP00000343129
ENST00000475051 ENSP00000433779
ENST00000526161
ENST00000530919
ENST00000524664
ENST00000525887
ENST00000533302 ENSP00000437078
ENST00000531555 ENSP00000433122
ENST00000524816 ENSP00000431869
ENST00000525327 ENSP00000432285
ENST00000528870 ENSP00000435696
ENST00000529044 ENSP00000436015
ENST00000524956 ENSP00000431790
ENST00000526881 ENSP00000436279
ENST00000530470
ENST00000532195
ENST00000529011 ENSP00000435600
ENST00000529495 ENSP00000433324
ENST00000532833 ENSP00000436567
ENST00000529040 ENSP00000433084
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
Experimentally validated
Total 47 [view]
Protein-Protein 47 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:1900181 negative regulation of protein localization to nucleus
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032013
View Gene Order
ENSBTAG00000009419
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.626329
RefSeq NM_012101 XM_005271487 XM_005271490
HUGO
OMIM
CCDS CCDS8428
HPRD 10280
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca