Homo sapiens Gene: DCAF17
Summary
InnateDB Gene IDBG-74898.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCAF17
Gene Name DDB1 and CUL4 associated factor 17
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000115827
Encoded Proteins
DDB1 and CUL4 associated factor 17
DDB1 and CUL4 associated factor 17
DDB1 and CUL4 associated factor 17
DDB1 and CUL4 associated factor 17
DDB1 and CUL4 associated factor 17
DDB1 and CUL4 associated factor 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nuclear transmembrane protein that associates with cullin 4A/damaged DNA binding protein 1 ubiquitin ligase complex. Mutations in this gene are associated with Woodhouse-Sakati syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:171434217-171485052
Strand Forward strand
Band q31.1
Transcripts
ENST00000375255 ENSP00000364404
ENST00000339506 ENSP00000342160
ENST00000436317 ENSP00000400335
ENST00000431110 ENSP00000403992
ENST00000468592
ENST00000495925
ENST00000490217
ENST00000480855
ENST00000493106
ENST00000498486
ENST00000539783 ENSP00000442238
ENST00000611110 ENSP00000477604
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005730 nucleolus
GO:0016021 integral component of membrane
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.626473 Hs.659439
RefSeq NM_001164821 NM_025000 XM_006712767 XM_006712768 XM_006712770 XM_006712773
HUGO
OMIM
CCDS CCDS2243 CCDS54419
HPRD 08579
IMGT
EMBL
GenPept
RNA Seq Atlas