Homo sapiens Gene: CISD1
Summary
InnateDB Gene IDBG-74906.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CISD1
Gene Name CDGSH iron sulfur domain 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000122873
Encoded Proteins
CDGSH iron sulfur domain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:58269058-58289586
Strand Forward strand
Band q21.1
Transcripts
ENST00000333926 ENSP00000363041
ENST00000464703
ENST00000489785
ENST00000488388
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 7 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0043457 regulation of cellular respiration
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0016021 integral component of membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.370102 Hs.596912 Hs.623728 Hs.738144
RefSeq NM_018464 XM_006717916
HUGO
OMIM
CCDS CCDS7251
HPRD 12587
IMGT
EMBL
GenPept
RNA Seq Atlas