Homo sapiens Gene: FBXL18
Summary
InnateDB Gene IDBG-7542.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXL18
Gene Name F-box and leucine-rich repeat protein 18
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000155034
Encoded Proteins
F-box and leucine-rich repeat protein 18
F-box and leucine-rich repeat protein 18
F-box and leucine-rich repeat protein 18
F-box and leucine-rich repeat protein 18
F-box and leucine-rich repeat protein 18
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:5431335-5513798
Strand Reverse strand
Band p22.1
Transcripts
ENST00000382368 ENSP00000371805
ENST00000415009 ENSP00000415064
ENST00000458142 ENSP00000405896
ENST00000453700 ENSP00000444797
ENST00000620087 ENSP00000481397
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 80028
UniGene Hs.623974
RefSeq NM_024963 XM_005249853 XM_005249854
HUGO HGNC:21874
OMIM 609084
CCDS CCDS43546
HPRD 07753
IMGT
EMBL
GenPept
RNA Seq Atlas 80028