Homo sapiens Gene: ADO
Summary
InnateDB Gene IDBG-75614.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADO
Gene Name 2-aminoethanethiol (cysteamine) dioxygenase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181915
Encoded Proteins
2-aminoethanethiol (cysteamine) dioxygenase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:62804857-62808483
Strand Forward strand
Band q21.3
Transcripts
ENST00000373783 ENSP00000362888
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0047800 cysteamine dioxygenase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Taurine and hypotaurine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q96SZ5
TrEMBL
UniProt Splice Variant
Entrez Gene 84890
UniGene Hs.627282 Hs.99821
RefSeq NM_032804
HUGO HGNC:23506
OMIM 611392
CCDS CCDS7266
HPRD 12566
IMGT
EMBL AK027453 AL133417 BC018660 BC028589 BC067740 CH471083
GenPept AAH18660 AAH28589 AAH67740 BAB55123 CAH73826 EAW54235
RNA Seq Atlas 84890