Version 5.4
Homo sapiens Gene: ATOH7
Summary
InnateDB Gene IDBG-75985.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATOH7
Gene Name atonal homolog 7 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000179774
Encoded Proteins
IDBP-75987
atonal homolog 7 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:68230624-68232103
Strand Reverse strand
Band q21.3
Transcripts
ENST00000373673 ENSP00000362777
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0003407 neural retina development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007623 circadian rhythm
GO:0009649 entrainment of circadian clock
GO:0021554 optic nerve development
GO:0030154 cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036816
View Gene Order
ENSBTAG00000017521
Not yet available
Cross-References
SwissProt Q8N100
TrEMBL F1T0H4
UniProt Splice Variant
Entrez Gene 220202
UniGene Hs.175396 Hs.606763 Hs.737072
RefSeq NM_145178
HUGO HGNC:13907
OMIM 609875
CCDS CCDS7276
HPRD
IMGT
EMBL AB593108 AB593109 AF418922 BC032621 BK000277 CH471083
GenPept AAH32621 AAL11911 BAJ84048 BAJ84049 DAA01057 EAW54269
RNA Seq Atlas 220202

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca