Homo sapiens Gene: SAMSN1
Summary
InnateDB Gene IDBG-762.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SAMSN1
Gene Name SAM domain, SH3 domain and nuclear localization signals 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000155307
Encoded Proteins
SAM domain, SH3 domain and nuclear localization signals 1
SAM domain, SH3 domain and nuclear localization signals 1
SAM domain, SH3 domain and nuclear localization signals 1
SAM domain, SH3 domain and nuclear localization signals 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:14485228-14583402
Strand Reverse strand
Band q11.2
Transcripts
ENST00000285670 ENSP00000285670
ENST00000400566 ENSP00000383411
ENST00000400564 ENSP00000383409
ENST00000463807
ENST00000493640
ENST00000619120 ENSP00000480850
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001784 phosphotyrosine binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0002820 negative regulation of adaptive immune response
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0050869 negative regulation of B cell activation
Cellular Component
GO:0001726 ruffle
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9NSI8
TrEMBL S6FRS6
UniProt Splice Variant
Entrez Gene 64092
UniGene Hs.473341 Hs.719474
RefSeq NM_001256370 NM_001286523 NM_022136
HUGO HGNC:10528
OMIM 607978
CCDS CCDS42906 CCDS58786 CCDS74774
HPRD
IMGT
EMBL AF165138 AF218085 AF222927 AF519621 AK125144 AL163206 BC029112 HG380514
GenPept AAG23355 AAH29112 AAK07746 AAM75349 BAG54155 CAB90391 CDG37814
RNA Seq Atlas 64092