Version 5.4
Homo sapiens Gene: BICD2
Summary
InnateDB Gene IDBG-76295.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BICD2
Gene Name bicaudal D homolog 2 (Drosophila)
Synonyms bA526D8.1; SMALED2
Species Homo sapiens
Ensembl Gene ENSG00000185963
Encoded Proteins
IDBP-76297
bicaudal D homolog 2 (Drosophila)
IDBP-76299
bicaudal D homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:92711363-92764812
Strand Reverse strand
Band q22.31
Transcripts
ENST00000356884 ENSP00000349351
ENST00000375512 ENSP00000364662
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
Biological Process
GO:0006810 transport
GO:0007018 microtubule-based movement
GO:0008219 cell death
GO:0072385 minus-end-directed organelle transport along microtubule
GO:0072393 microtubule anchoring at microtubule organizing center
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037933
View Gene Order
ENSBTAG00000046549
Not yet available
Cross-References
SwissProt Q8TD16
TrEMBL
UniProt Splice Variant
Entrez Gene 23299
UniGene Hs.436939 Hs.623027 Hs.626910
RefSeq NM_001003800 NM_015250
HUGO HGNC:17208
OMIM 609797
CCDS CCDS35064 CCDS6700
HPRD
IMGT
EMBL AB014599 AL136981 AL137074 AY052562 BC004296 BC073970
GenPept AAH04296 AAH73970 AAL12246 BAA31674 CAI14369 CAI14370 CAI41013 CAI41014
RNA Seq Atlas 23299

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca