Homo sapiens Gene: KCNS1
Summary
InnateDB Gene IDBG-77217.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNS1
Gene Name potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
Synonyms KV9.1;
Species Homo sapiens
Ensembl Gene ENSG00000124134
Encoded Proteins
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:45092310-45101112
Strand Reverse strand
Band q13.12
Transcripts
ENST00000306117 ENSP00000307694
ENST00000537075 ENSP00000445595
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005515 protein binding
GO:0015459 potassium channel regulator activity
Biological Process
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Neuronal System pathway
Voltage gated Potassium channels pathway
Potassium Channels pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.117780
RefSeq NM_002251 XM_005260409
HUGO
OMIM
CCDS CCDS13342
HPRD 04214
IMGT
EMBL
GenPept
RNA Seq Atlas