Version 5.4
Homo sapiens Gene: SRSF8
Summary
InnateDB Gene IDBG-774316.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRSF8
Gene Name serine/arginine-rich splicing factor 8
Synonyms DSM-1; SFRS2B; SRP46
Species Homo sapiens
Ensembl Gene ENSG00000263465
Encoded Proteins
IDBP-808861
serine/arginine-rich splicing factor 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:95067197-95071224
Strand Forward strand
Band q21
Transcripts
ENST00000587424 ENSP00000480140
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q9BRL6
TrEMBL A0A024R3A8
UniProt Splice Variant
Entrez Gene 10929
UniGene
RefSeq NM_032102
HUGO HGNC:16988
OMIM 603269
CCDS CCDS73370
HPRD
IMGT
EMBL AF031165 AF031166 AK023379 AK312514 BC057783 CH471065
GenPept AAH57783 AAK54350 AAK54351 BAG35415 BAG51186 EAW66954 EAW66955 EAW66956
RNA Seq Atlas 10929

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca