Version 5.4
Homo sapiens Gene: CCL4L1
Summary
InnateDB Gene IDBG-776845.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCL4L1
Gene Name chemokine (C-C motif) ligand 4-like 1
Synonyms AT744.2; CCL4L; SCYA4L; SCYQ4L2
Species Homo sapiens
Ensembl Gene ENSG00000276070
Encoded Proteins
IDBP-812205
chemokine (C-C motif) ligand 4-like 1
IDBP-812206
chemokine (C-C motif) ligand 4-like 1
IDBP-812207
chemokine (C-C motif) ligand 4-like 1
IDBP-812210
chemokine (C-C motif) ligand 4-like 1
IDBP-812211
chemokine (C-C motif) ligand 4-like 1
IDBP-812212
chemokine (C-C motif) ligand 4-like 1
IDBP-812213
chemokine (C-C motif) ligand 4-like 1
IDBP-812215
chemokine (C-C motif) ligand 4-like 1
IDBP-812218
chemokine (C-C motif) ligand 4-like 1
IDBP-812221
chemokine (C-C motif) ligand 4-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. This gene copy contains a non-consensus splice acceptor site at the 3\' terminal exon found in other highly similar gene copies, and it thus uses other alternative splice sites for the 3\' terminal exon, resulting in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:36210924-36212878
Strand Forward strand
Band q12
Transcripts
ENST00000615418 ENSP00000483206
ENST00000617416 ENSP00000480089
ENST00000613173 ENSP00000484455
ENST00000620732 ENSP00000481969
ENST00000620098 ENSP00000479774
ENST00000620576 ENSP00000479354
ENST00000620055 ENSP00000481323
ENST00000617405 ENSP00000483330
ENST00000610565 ENSP00000484498
ENST00000620250 ENSP00000483609
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
Biological Process
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0060326 cell chemotaxis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001001435 NM_001291468 NM_001291469 NM_001291470 NM_001291471 NM_001291472 NM_001291473 NM_001291474 NM_001291475
HUGO
OMIM
CCDS CCDS32627
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca