Version 5.4
Homo sapiens Gene: TDRD7
Summary
InnateDB Gene IDBG-77714.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TDRD7
Gene Name tudor domain containing 7
Synonyms CATC4; CTRCT36; PCTAIRE2BP; TRAP
Species Homo sapiens
Ensembl Gene ENSG00000196116
Encoded Proteins
IDBP-77718
tudor domain containing 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs. Mutation in this gene has been associated with pediatric cataracts. Mutation of the similar gene in mice has been associated with cataracts, glaucoma and a block in spermatogenesis. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:97411950-97496125
Strand Forward strand
Band q22.33
Transcripts
ENST00000355295 ENSP00000347444
ENST00000492428
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0002089 lens morphogenesis in camera-type eye
GO:0007281 germ cell development
GO:0007283 spermatogenesis
GO:0010608 posttranscriptional regulation of gene expression
GO:0070306 lens fiber cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0005759 mitochondrial matrix
GO:0030529 ribonucleoprotein complex
GO:0033391 chromatoid body
GO:0035770 ribonucleoprotein granule
GO:0043186 P granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035517
View Gene Order
ENSBTAG00000003719
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
aurora_a_pathway
Aurora A signaling
Cross-References
SwissProt Q8NHU6
TrEMBL
UniProt Splice Variant
Entrez Gene 23424
UniGene Hs.193842
RefSeq NM_014290 XM_006717025
HUGO HGNC:30831
OMIM 611258
CCDS CCDS6725
HPRD
IMGT
EMBL AB025254 AK294488 AK301954 AK314853 AL122110 AL449464 AL512590 BC028694 CH471105
GenPept AAH28694 BAA76379 BAG37370 BAG57710 BAG63369 CAB59271 CAH71605 CAI14933 EAW58844
RNA Seq Atlas 23424

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca