Version 5.4
Homo sapiens Gene: DNAL4
Summary
InnateDB Gene IDBG-7793.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAL4
Gene Name dynein, axonemal, light chain 4
Synonyms PIG27
Species Homo sapiens
Ensembl Gene ENSG00000100246
Encoded Proteins
IDBP-7795
dynein, axonemal, light chain 4
IDBP-293508
dynein, axonemal, light chain 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary DNAL4 is a component of the dynein motor complex (Iwasaki et al., 2005 [PubMed 15454493]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:38778508-38794198
Strand Reverse strand
Band q13.1
Transcripts
ENST00000216068 ENSP00000216068
ENST00000406199 ENSP00000385712
ENST00000486019
ENST00000475512
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
Biological Process
GO:0007017 microtubule-based process
GO:0008152 metabolic process
GO:0048011 neurotrophin TRK receptor signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0030286 dynein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022420
View Gene Order
ENSBTAG00000026495
Not yet available
Pathways
NETPATH
REACTOME
REACT_12435
Retrograde neurotrophin signalling pathway
REACT_11061
Signalling by NGF pathway
REACT_111102
Signal Transduction pathway
REACT_12056
NGF signalling via TRKA from the plasma membrane pathway
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL B0QXZ5
UniProt Splice Variant
Entrez Gene 10126
UniGene Hs.622582
RefSeq NM_005740
HUGO HGNC:2955
OMIM 610565
CCDS CCDS13979
HPRD 13239
IMGT
EMBL AL008583
GenPept
RNA Seq Atlas 10126

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca