Version 5.4
Homo sapiens Gene: EEF1B2
Summary
InnateDB Gene IDBG-79451.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EEF1B2
Gene Name eukaryotic translation elongation factor 1 beta 2
Synonyms EEF1B; EEF1B1; EF1B
Species Homo sapiens
Ensembl Gene ENSG00000114942
Encoded Proteins
IDBP-79453
eukaryotic translation elongation factor 1 beta 2
IDBP-246098
eukaryotic translation elongation factor 1 beta 2
IDBP-246100
eukaryotic translation elongation factor 1 beta 2
IDBP-388562
eukaryotic translation elongation factor 1 beta 2
IDBP-388563
eukaryotic translation elongation factor 1 beta 2
IDBP-388564
eukaryotic translation elongation factor 1 beta 2
IDBP-388565
eukaryotic translation elongation factor 1 beta 2
IDBP-388566
eukaryotic translation elongation factor 1 beta 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008]
This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5\' UTR. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:206159585-206162928
Strand Forward strand
Band q33.3
Transcripts
ENST00000236957 ENSP00000236957
ENST00000392222 ENSP00000376056
ENST00000392221 ENSP00000376055
ENST00000445505 ENSP00000407730
ENST00000429769 ENSP00000397793
ENST00000415904 ENSP00000393501
ENST00000455150 ENSP00000387407
ENST00000435123 ENSP00000399917
ENST00000479587
ENST00000460760
ENST00000482103
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 55 [view]
Protein-Protein 54 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003746 translation elongation factor activity
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0010467 gene expression
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005829 cytosol
GO:0005853 eukaryotic translation elongation factor 1 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025967
View Gene Order
ENSBTAG00000021979
Not yet available
Pathways
NETPATH
REACTOME
REACT_1477
Eukaryotic Translation Elongation pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.627033 Hs.742407
RefSeq NM_001037663 NM_001959 NM_021121
HUGO
OMIM
CCDS CCDS2367
HPRD 02804
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca