Homo sapiens Gene: ARMCX2
Summary
InnateDB Gene IDBG-79858.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARMCX2
Gene Name armadillo repeat containing, X-linked 2
Synonyms ALEX2; GASP9;
Species Homo sapiens
Ensembl Gene ENSG00000184867
Encoded Proteins
armadillo repeat containing, X-linked 2
armadillo repeat containing, X-linked 2
armadillo repeat containing, X-linked 2
armadillo repeat containing, X-linked 2
armadillo repeat containing, X-linked 2
armadillo repeat containing, X-linked 2
armadillo repeat containing, X-linked 2
armadillo repeat containing, X-linked 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX1 and ALEX3, on the X chromosome. Two alternative transcripts that encode the same protein but differ in the 5' UTR have been described. Additional alternative transcripts may exist but their full length natures have not been determined. A pseudogene for this locus is located on chromosome 7. [provided by RefSeq, Jul 2008]
This gene encodes a protein containing a potential N-terminal transmembrane domain and multiple armadillo (arm) repeats. Proteins containing arm repeats are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is located in a cluster of related genes on chromosome X. There is a pseudogene for this gene on chromosome 7. Alternative splicing in the 5\' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome X:101655281-101659891
Strand Reverse strand
Band q22.1
Transcripts
ENST00000328766 ENSP00000331662
ENST00000330154 ENSP00000328631
ENST00000356824 ENSP00000349281
ENST00000413506 ENSP00000412481
ENST00000433318 ENSP00000410151
ENST00000440675 ENSP00000393778
ENST00000458024 ENSP00000415490
ENST00000431597 ENSP00000405376
ENST00000467416
ENST00000479333
ENST00000496581
ENST00000488982
ENST00000475854
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.48924 Hs.618522 Hs.727184
RefSeq NM_001282231 NM_014782 NM_177949 XM_005278109 XM_005278110 XM_005278111 XM_005278113 XM_005278114 XM_005278115 XM_005278116 XM_005278117
HUGO
OMIM
CCDS CCDS14490
HPRD 02293
IMGT
EMBL
GenPept
RNA Seq Atlas