InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPS24

Summary

InnateDB Gene

IDBG-79966.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPS24

Gene Name

ribosomal protein S24

Synonyms

DBA3; S24

Species

Homo sapiens

Ensembl Gene

ENSG00000138326

Encoded Proteins

IDBP-79968

ribosomal protein S24

IDBP-79970

ribosomal protein S24

IDBP-381091

ribosomal protein S24

IDBP-381092

ribosomal protein S24

IDBP-811800

ribosomal protein S24

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S24E family of ribosomal proteins. It is located in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. [provided by RefSeq, Nov 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:78033760-78056812

Strand

Forward strand

Band

q22.3

Transcripts

ENST00000360830	ENSP00000354074
ENST00000372360	ENSP00000361435
ENST00000440692	ENSP00000414321
ENST00000435275	ENSP00000415549
ENST00000485708
ENST00000478655
ENST00000464716
ENST00000476545
ENST00000466129
ENST00000475468
ENST00000482069
ENST00000465692
ENST00000480662
ENST00000613865	ENSP00000478869

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 147 experimentally validated interaction(s) in this database.

Experimentally validated
Total	147 [view]
Protein-Protein	147 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003735	structural constituent of ribosome
GO:0031369	translation initiation factor binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0034101	erythrocyte homeostasis
GO:0042274	ribosomal small subunit biogenesis
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022627	cytosolic small ribosomal subunit