Version 5.4
Homo sapiens Gene: FKBPL
Summary
InnateDB Gene IDBG-80270.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FKBPL
Gene Name FK506 binding protein like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000204315
Encoded Proteins
IDBP-80272
FK506 binding protein like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:32128707-32130291
Strand Reverse strand
Band p21.32
Transcripts
ENST00000375156 ENSP00000364298
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 53 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 53 [view]
Protein-Protein 52 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding
GO:0005528 FK506 binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0009314 response to radiation
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033739
View Gene Order
ENSBTAG00000037781
Not yet available
Cross-References
SwissProt Q9UIM3
TrEMBL A0A024RCQ6
UniProt Splice Variant
Entrez Gene 63943
UniGene Hs.520042
RefSeq NM_022110
HUGO HGNC:13949
OMIM
CCDS CCDS4738
HPRD 16901
IMGT
EMBL AF139374 AK027119 AK291418 AL662828 AL662884 BC004168 BC011966 CH471081 CR457374 CR753803 CR925796 U89337
GenPept AAF04864 AAF67785 AAH04168 AAH11966 BAB15663 BAF84107 CAG33655 CAI17420 CAI18338 CAQ09554 CAQ10265 EAX03586 EAX03587
RNA Seq Atlas 63943

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca