Version 5.4
Homo sapiens Gene: GPRASP2
Summary
InnateDB Gene IDBG-80341.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPRASP2
Gene Name G protein-coupled receptor associated sorting protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000158301
Encoded Proteins
IDBP-80343
G protein-coupled receptor associated sorting protein 2
IDBP-598274
G protein-coupled receptor associated sorting protein 2
IDBP-596569
G protein-coupled receptor associated sorting protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring armadillo repeat containing, X-linked 5 and G protein-coupled receptor associated sorting protein 2 genes on chromosome X. The read-through transcript produces a protein identical to protein encoded by the downstream locus, G protein-coupled receptor associated sorting protein 2. [provided by RefSeq, Dec 2010] The protein encoded by this gene is a member of a family that regulates the activity of G protein-coupled receptors (GPCRs). The encoded protein has been shown to be capable of interacting with several GPCRs, including the M1 muscarinic acetylcholine receptor and the calcitonin receptor. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:102712176-102717733
Strand Forward strand
Band q22.1
Transcripts
ENST00000332262 ENSP00000339057
ENST00000483720
ENST00000486814
ENST00000543253 ENSP00000437872
ENST00000535209 ENSP00000437394
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
Experimentally validated
Total 59 [view]
Protein-Protein 59 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001540 beta-amyloid binding
GO:0005488 binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSMUSG00000072966
View Gene Order
Ortholuge
SSD Ortholog
Ortholog supports species divergence
ENSBTAG00000032852
Not yet available
Ortholuge
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q96D09
TrEMBL
UniProt Splice Variant
Entrez Gene 114928
UniGene Hs.522729 Hs.715086 Hs.731996 Hs.741410
RefSeq NM_001184875 NM_001004051 NM_001184874 NM_001184876 NM_001199818 NM_138437
HUGO HGNC:25169
OMIM
CCDS CCDS14501
HPRD 06612
IMGT
EMBL AK092981 AL035427 BC013576 BC036772 CH471190
GenPept AAH13576 AAH36772 CAI43060 EAW54727 EAW54728 EAW54729
RNA Seq Atlas 100528062 114928

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca